125 / 2019-11-04 21:00:58

Epidemiology and spatial characteristics in rate of different serum levels of anti-hepatitis B surface antibodies in college students in a University in Hunan Province, China

HBsAb, spatial characteristics, college student, Hunan Province, Sex difference

This study aimed to demonstrate the epidemiology and spatial characteristics in rate of different serum levels of anti-hepatitis B surface antibodies (HBsAb) in college students in a University in Hunan Province, China. A total of 4648 college students with complete data of serum levels of anti-hepatitis B surface antibodies and geographic information were included in the present study. Subjects were categorized into three groups according to the serum level of HBsAb: negative, weak positive, and positive. Totally, 46.9% of the students were HBsAb negative, 36.4% weak positive (35.9% and 36.6% for males and females, respectively), 16.7% positive (17.7% and 16.3% for males and females, respectively). There is a significant difference in the geographic distribution of the serum level of HBsAb of the study population. Also, we found a sex difference in the clustering of low-low area of rate of HBsAb (+) in Hunan Province. It is likely that we should develop area-specific and sex-specific intervention and prevention strategies for different areas of the Hepatitis B infection in Hunan Province, China.