The safety production situation in our country is still severe. Improving the emergency response capacity for production safety accidents is the foundation for quickly controlling the situation and scientific rescue. The emergency response network is a network structure formed by multiple entities. Guided by common goals, each entity carries out response actions in their respective professional fields, but also requires communication and exchange across professional boundaries to gain understanding and mutual trust, ultimately achieving common goals. In the process of cross disciplinary communication, a very important resource is knowledge. This article takes the "structure process" of emergency response to safety production accidents as the framework, analyzes the subject object structure and key knowledge management processes of knowledge management in emergency response from the perspective of knowledge management, and constructs a knowledge management model for emergency response to safety production accidents. Using grounded theory, 40 production safety accident investigation reports released by the emergency management department are analyzed to verify the rationality of the model.