This study investigates the skincare benefits of Iranian Beluga sturgeon caviar, rich in bioactive compounds such as essential fatty acids, peptides, vitamins, and minerals. The caviar protein was enzymatically hydrolyzed on an industrial scale, and peptides were separated by ultrafiltration. Antioxidant activity was measured using DPPH and ABTS assays, showing significant free radical scavenging. At 1 mg/mL, the total hydrolysate inhibited 45.59% of DPPH and 71.24% of ABTS radicals, while the <3 kDa peptide fraction inhibited 23.35% and 82.19%, respectively. Human foreskin fibroblasts treated with these hydrolysates demonstrated increased cell viability and enhanced type I collagen production, confirmed via immunocytochemistry. Under oxidative stress, fibroblast viability rose to 165.9% with total hydrolysate and 86.16% with the low-molecular-weight fraction at 25 μg/mL. Both treatments significantly stimulated collagen synthesis, indicating potential for anti-aging skincare. Based on these findings, three cream formulations were developed: a hydrating eye contour cream targeting wrinkles, an anti-blemish product to reduce inflammation and even skin tone, and a brightening cream to enhance radiance through antioxidant and collagen-boosting effects. These products were tested on 48 volunteers aged 38 to 45, showing clear improvements in wrinkle reduction, skin smoothness, and brightness. This work demonstrates the promising role of hydrolyzed sturgeon caviar peptides as natural, effective ingredients for advanced skincare products, combining traditional luxury with scientific validation to support skin rejuvenation and anti-aging care.
 

Sturgeon caviar, Iranian Beluga, Hydrolyzed protein, Antioxidant activity, Collagen synthesis, Anti-aging skincare