Uncertainty quantification (UQ) is essential for producing informative computational predictions in a wide range of sciences and engineering. The field relies on a broad range of mathematical and statistical foundations, with associated algorithmic and computational developments. This conference will bring together mathematicians, statisticians, scientists, and engineers with an interest in the development and implementation of uncertainty quantification methods. Major conference themes will include the mathematical and statistical foundations of UQ, applications of UQ in the physical sciences and biosciences, and connections between UQ and machine learning. The goal of the meeting is to provide a forum to share ideas and enhance communication among this diverse group of technical experts, thereby contributing to future advances in the field.