We solicit high-quality original research papers (including significant work-in-progress) in any aspect of bioinformatics and biomedicine. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged