The Technical Committee on Multiple-Valued Logic of the IEEE Computer Society will hold its 45th annual symposium in Waterloo, Ontario, Canada, on May 18-20, 2015. The Conference will bring together researchers from computer science, engineering, mathematics, and further disciplines to discuss new developments and directions for future research in the area of multi-valued logic and related fields. Research papers, surveys, or tutorial papers on any subject in these areas are within the scope of the symposium.