Established in 1992, ICPADS has been a major international forum for scientists, engineers, and users to exchange and share their experiences, new ideas, and latest research results on all aspects of parallel and distributed computing systems. The 21st IEEE International Conference on Parallel and Distributed Systems (ICPADS 2015) will be held in Melbourne, Australia, December 14 – 17, 2015. The main conference will run from December 15 to 17, and all the workshops will run on December 14. The conference venue is RMIT University's city campus, right in the CBD of Melbourne.