IEEE System, Man, and Cybernetics Society and IEEE Reliability Society announce the 12th International Conference on System of Systems Engineering (SoSE) with its vast ramifications in numerous engineering fields such as control, computing, communication, information technology and in applications such manufacturing, defense, national security, aerospace, aeronautics, energy, environment, healthcare, and transportation. The conference theme is “Internet of Things as System of Systems”. Papers on theories, methodologies, and applications of System of Systems Engineering in science, technology, industry, and education are welcome.